Archive for the ‘Therapy’ Category
Today, viruses are the vectors used for these tests, as can be genetically altered to no longer be carrying pathogens and genes in other organisms. However, there are other vectors of viral origin have also been used to it.
A gene vector is used in therapy, and which due to the diversity of situations that could be applied, must comply with the following characteristics:
• It is reproducible, stable and allows the insertion of genetic material regardless of size, and is easy to produce and store.
• To enable transduction in both dividing cells and in those that are not proliferating.
• That it is possible to integrate the therapeutic gene specific.
• It can recognize and act on specific cells.
• The therapeutic gene expression can be regulated. Read the rest of this entry »
Gene therapy involves the insertion of working copies of genes to replace those with defective or absent in the genome of an individual. This therapy is carried out in cells and tissues to treat a severe illness, acquired or hereditary.
The approaches currently available for this therapy are very different but in most studies is called gene therapy when copying adding the gene which is inserted into the genome and is introduced only in the host to compensate for the defective . On the other hand, in the case of homologous recombination, ie, to remove and replace the defective copy of the functional is replacement therapy.
Gene therapy, which is still in development, consider the following factors: Read the rest of this entry »