Archive for the ‘Anticoagulant’ Category
Mechanism of action:
- Under normal conditions, blood flows through the circulatory system without clot. However, naturally has the ability to coagulate in certain situations, such as when we cut, to plug a wound. Thrombi and emboli are a pathological consequence of the ability of blood to clot.
- Anticoagulant medication works by lengthening the time it takes blood to clot by interfering with vitamin K action is in the coagulation and so difficult that may form thrombi or emboli. For the protection is adequate must achieve a certain time because if we drag it little protection will be inadequate and if we drag it too will be well protected from the thrombus but with an excessive risk of bleeding. Read the rest of this entry »
In recent years have increased very important indications for anticoagulant medication.
The large number of patients who take anticoagulants daily and the particularities of their control have led us to produce this guide in order to give a clear answer simple questions in our experience most frequently raised by patients, the idea of made easier to understand the reasons for the treatment and control and give some simple instructions that give you maximum benefit with minimum risk.
The goal of treatment
The goal of treatment is prevention of thrombosis and embolism. A thrombus is a clot within the circulatory system. It is said that a stroke occurs when a fragment of the clot breaks off and clogs suddenly a vein or artery.
Since this is the goal, patients who benefit from this preventive treatment are: Read the rest of this entry »
Thromboembolic disease (TED), deep vein thrombosis (DVT) and thromboembolism (PTE)
Thromboembolic disease risk factors:
- Surgery
- Trauma (higher or lower extremity)
- Immobility (> 72 hours), paralysis / paresis
- Malignancy
- Cancer Treatment
- Prior thromboembolic disease
- Age
- Pregnancy and Postpartum
- Contraceptive hormone treatment and estrogen component
- Acute medical illness
- Cardiac or respiratory failure
- Inflammatory bowel disease
- Nephrotic syndrome
- Myeloproliferative disease
- Obesity
- Smoking
- Congenital or acquired thrombophilia
- Varicose Veins
- Central venous catheterization Read the rest of this entry »
Treatment with oral anticoagulants (OAC) has been used for years with proven effectiveness in primary and secondary prophylaxis of thromboembolic disease. To this should be maintained adequate anticoagulation level, and that deviations can cause serious or fatal complications, which requires constant clinical surveillance and analytics.
OCs are derivatives of coumarin and act as antagonists of the VIT-K, the most commonly used are warfarin.
Standardizing the prothrombin time measurement by the INR (International Normalized Ratio), lower-range anticoagulation indicated with a consequent reduction of bleeding complications, the possibility of determining the INR in capillary blood and the development of Primary Care (PC ) make it possible to monitor these patients at this level of care. Read the rest of this entry »